We developed ion chromatography (IC) assays for ammonia, chloride, and sulfate in
adenosine. The assays require <5 min per sample and accurately determine the ions
by suppressed conductivity detection. These IC-based assays meet the analytical
performance characteristics outlined in U.S. Pharmacopeia (USP) General Chapter
, Validation of Compendial Procedures and can replace that monographʼs
visual-comparison-based methods.
United States
