Santosh A. Misal1, Yongzheng Cong1, Amanda J. Guise2, Khatereh Motamedchaboki3, Yiran Liang1, Thy Truong1, Romain Huguet3, Daniel Lopez-Ferrer3, Edward D. Plowey3, Ying Zhu4, Edward D. Plowey2, Ryan T. Kelly1
International Hupo 2020
Single-cell analysis can reveal cellular heterogeneity that is obscured by bulk measurements. Recently developed nanoPOTS workflow with ultrasensitive mass spectrometry resolves the heterogeneity and enables the discovery of cellular and molecular mechanisms related to various disease and developmental processes.
1Department of Chemistry and Biochemistry, Brigham Young, University, Provo, UT 84602, USA. 2Biogen Inc., Cambridge, MA 02142, 3Thermo Fisher Scientific, San Jose, CA, 4Pacific Northwest National Laboratory, Richland, WA