Denisov E, Damoc E, Zeller M, Müller M, Kuipers H, Griep-Raming J, Makarov A, Nolting D, Möhring T.
ASMS 2012 Poster
Purpose: Modifications to a standard ion trap-OrbitrapTM hybrid instrument for improved intact protein and top-down analysis.
Methods: Improvement in Orbitrap mass analyzer vacuum and higher trapping efficiency by trapping in HCD cell.
Results: Higher S/N of intact protein signal and higher sequence coverage for top-down analyses.
Thermo Fisher Scientific
United States
