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Improvements for high resolution analysis on a modified Tribrid mass spectrometer

Reputable Mentor II
Reputable Mentor II
Canterbury J, Izgarian N, Senko M, Stratton T, Sharma S, Kiyonami R, Denisov E, Makarov A.
ASMS 2015 Poster
Purpose: This work shows improvements in Orbitrap analysis, especially with respect to peak coalescence and resolution. Methods: A Thermo ScientificTM Orbitrap FusionTM TribridTM mass spectrometer was modified by (1) improvements to the vacuum system aimed at reducing the amount of gas in the ion injection region and (2) careful matching of Orbitrap electrodes. Results: Improvements in coalescence performance, resolution, and in examples from applications in top-down proteomics, lipidomics, and metabolomics are observed.

Thermo Fisher Scientific
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Last update:
‎10-15-2021 12:05 PM
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