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Improved Identification, Quantification Accuracy, and Workflow Efficiency using a Modified Quadrupole Orbitrap Mass Spectrometer and Tandem Mass Tags (TMT) Approach

Reputable Mentor II
Reputable Mentor II
Aaron M. Robitaille 1, Tabiwang N. Arrey 2, Markus Kellmann 2, Arne Kreutzmann 2, Daniel Mourad 2, Daniel Lopez Ferrer 1, Andreas Huhmer 1, Alexander Harder 2

Multiplexed quantitation strategies using Thermo Scientific™ Tandem Mass Tags™ (TMT™) enable precise measurement of peptide or protein abundance from multiple samples into a single high-resolution LC-MS analysis. Increasingly, various biological experiments demand higher quantitation accuracy and proteome coverage. Here, we demonstrate increased quantitative performance and throughput efficiency on a Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer combined with a Thermo Scientific™ FAIMS Pro™ interface.

1 Thermo Fisher Scientific, 355 River Oaks Pkwy, San Jose, CA 95134. 2 Thermo Fisher Scientific Hanna-Kunath-Straße 11, 28199 Bremen, Germany
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Last update:
‎10-15-2021 10:53 AM
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