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Team TFS
Team TFS
The multiple pathways from which perchlorate may be ingested into the body and its associated health risks has increased the interest in the determination of low concentrations of perchlorate. Perchlorate inhibits the normal
uptake of iodide by the thyroid gland, which results in reduced thyroid hormone production. Low thyroid hormone production results in improper metabolic regulation and can potentially lead to the development of thyroid tumors in adults.1,2 The fetuses of pregnant
women with hypothyroidism are particularly at higher risk because reduced thyroid hormone production can cause impaired mental development, and in some cases birth defects.1,3 In 2005, the National Academy of Sciences
recommended a reference dose of 0.7 µg/kg/day from all available sources, which it believes should not threaten the health of even the most sensitive populations.
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Last update:
‎10-16-2013 07:40 AM
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