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Reputable Mentor II
Reputable Mentor II
Christian Thoeing, Sebastien Gallien, Tabiwang Arrey, Yue Xuan, Oliver Lange, Kerstin Strupat , Markus Kellmann

Purpose: On-the-fly correction of scheduled retention time windows in order to allow more reliable profiling of more peptide targets Methods: Dynamic retention time window correction for scheduled PRM was applied fully unattended and automated on a Thermo Scientific™ Q Exactive™ HF-X hybrid quadrupole-Orbitrap™ mass spectrometer. Results: The dynamic correction of scheduled retention time windows in nano-LC setups allows for decreasing retention time windows to 60 seconds with increased reliability compared to static retention time window scheduling. This reduces the degree of overlapping of retention time windows, which in turn increases the amount of peptide targets that can be scheduled in an experiment.

Thermo Fisher Scientific, Bremen, Germany
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Last update:
‎10-15-2021 08:42 AM
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