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todd-linden
Team TFS
Team TFS
Although D-enatiomers of amino acids are common in lower organisms such as bacteria and not thought to occur in mammalian tissues, it has became apparent that
some D-amino acids do occur in higher organisms and have biochemical importance. Recent publications indicating an abundance of D-amino acids in neuroendocrine tissues have prompted the development of
simple analytical methods for the measurement of these amino acid enantiomers. D-serine (D-Ser) occurs in glial cells, is particularly abundant in brain regions enriched in NMDA receptors, and is the endogenous coagonist of the NMDA receptor (not glycine). D-aspartic acid (D-Asp)
is found in some specific neuronal pathways, but is more abundant in epinephrine-containing glandular tissue (e.g., adrenal medulla), where it appears to regulate hormone synthesis and release.
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Last update:
‎03-24-2014 05:51 PM
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