Chromatographic peak resolution is critical for peak integration which improves accurate quantification, identification, and reporting accuracy. However, the need for fast analysis times and high sample throughput often necessitates sacrificing peak resolution, risking the reliability of the results reported. In the latest generation of ion chromatography columns, the resin particles were optimized to an average distribution of 4 µm from the earlier 7–9 µm particles. The resultant ion-exchange columns have very high plate counts, 8k–12k plates/column, which increase peak resolution of critical pairs. This allows fast separations while maintaining peak resolution in 150 mm length fast columns and allows increased peak resolution of complex samples using the 250 mm high efficiency columns.