Showing results for 
Search instead for 
Did you mean: 

Exploring an Orbitrap Analyzer for the Characterization of Intact Antibodies by Native Mass Spectrometry

Reputable Mentor II
Reputable Mentor II
Rosati S, Rose RJ, Thompson NJ, van Duijn E, Damoc E, Denisov E, Makarov A, Heck AJ.
Angew Chem Int Ed Engl. 2012 Nov 22.
Antibody profiling: Native mass spectrometry analysis of intact antibodies can be achieved with improved speed, sensitivity, and mass resolution by using a modified orbitrap instrument. Complex mixtures of monoclonal antibodies can be resolved and their glycan "fingerprints" can be profiled. Noncovalent interactions are maintained, thus allowing antibody-antigen binding to be measured.;jsessionid=9F9A3FA452BE9F69F54343...
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre and Utrecht Institute of Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH (The Netherlands)
Version history
Last update:
‎10-15-2021 09:28 AM
Updated by: