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Driving Efficiency in a High-Throughput Metabolic Stability Assay through a Generic High-Resolution Accurate Mass Method and Automated Data Mining

Team TFS
Team TFS
Improving analytical throughput is the focus of many
quantitative workflows being developed for early drug
discovery. For drug candidate screening, it is common
practice to use ultra-high performance liquid chromatography
(U-HPLC) coupled with triple quadrupole mass spectrometry.
This approach certainly results in short analytical
run times; however, in assessing the true throughput, all
aspects of the workflow needs to be considered, including
instrument optimization and the necessity to re-run
samples when information is missed.
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Last update:
‎10-16-2013 07:40 AM
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