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Development of a High Quality Intact Protein Standard for LC and MS Quality Control and Application Development

Reputable Mentor II
Reputable Mentor II
Helene L. Cardasis1, Rosa Viner2, Vikrant Gohil1, Kay Opperman3, Shane Bechler4, John Rogers3, Kelly Flook4, Egle Capkauske5, Kestutis Bargaila5, Agne Alminaite5, Viktorija Vitkovske5, Paul Haney3

Purpose : develop a high quality, reproducible intact protein standard for LC-MS QC and application development. Methods : expression and purification of recombinant proteins that meet MW, m/z distribution, purity, stability, reproducibility requirements of a sample used for LC and MS QC. Results: a high quality, recombinant intact protein mixture for LC-MS quality control and application development was developed.

1 - Thermo Fisher Scientific, Cambridge, MA 02139 2- Thermo Fisher Scientific, San Jose, CA 95134 3- Thermo Fisher Scientific, Rockford, IL 61101 4- Thermo Fisher Scientific, Sunnyvale, CA 94085 5- Thermo Fisher Scientific, Vilnius, Lithuania LT-02241
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Last update:
‎10-15-2021 12:03 PM
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