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Determination of Rosuvastatin in Human Plasma by SPE-LC-MS/MS Using SOLA and Accucore RP-MS column

Team TFS
Team TFS
A simple, rapid and sensitive procedure for the
determination of rosuvastatin in human plasma by liquid
chromatography-tandem mass spectrometry was developed
and evaluated. The drug was isolated from within the
plasma matrix using a Thermo Scientific SOLA 96 well
plate, and the components of the resultant extracts were
separated on a Thermo Scientific Accucore RP-MS column
under reversed-phase, gradient conditions. Detection was
performed on a triple quadrupole mass spectrometer under
positive polarity, heated electrospray ionisation (HESI)
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Last update:
‎10-16-2013 07:40 AM
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