Detecting low abundant endogenous cardiac steroids from biological fluids using a structure-based MSn approach on an Orbitrap Tribrid mass spectrometer

[Orbitrap_SciLib]

Reiko Kiyonami1 , Michael G. Harrington2 , Alfred N. Fonteh2 , Roger G. Biringer3 , and Andreas F. Huhmer1
APPLICATION NOTE 73235
To develop an unbiased discovery-to-targeted-verification approach to detect low abundant endogenous cardiac steroids from biological fluids with high confidence using a Thermo Scientific™ Orbitrap ID-X™ Tribrid™ mass spectrometer.


1 Thermo Fisher Scientific, San Jose, CA 2 Huntington Medical Research Institutes, Pasadena, CA 3 LECOM Bradenton, Bradenton, FL