on 05-01-201210:40 AM - edited on 11-09-202101:47 AM by usermigration2
Hu Q, Talaty N, Noll RJ, Cooks RG. Rapid Commun Mass Spectrom. 2006;20(22):3403-8. Desorption electrospray ionization (DESI) is implemented on an Orbitrap mass spectrometer. The ion source is described and applications which utilize the high-resolution capabilities of the Orbitrap are emphasized, including the characterization of peptides and active ingredients in pharmaceutical tablets. Measurements are made in less than 1 s at a resolution of 60,000. The implications of the data for the mechanisms of DESI are discussed.