Demonstrating High-Performance Quantitative Analysis of Benzodiazepines using Multiplexed SIM with High-Resolution, Accurate Mass Detection on the Q Exactive LC/MS

[todd-linden]

To demonstrate the feasibility of high sensitivity liquid chromatography-mass spectrometry (LC/MS) quantification of benzodiazepines in urine by combining multiplexed SIM with high-resolution, accurate mass detection on the Q Exactive high-performance benchtop quadrupole-Orbitrap mass spectrometer.