IC is a commonly used analytical approach for determination of anionic and cationic species. IC coupled to inductively coupled plasma mass spectrometry (ICP-MS) is ideally suited for challenging applications such as arsenic speciation in food samples and Cr speciation in drinking water. The Dionex ICS-5000 ion chromatography system coupled to the iCAP Q ICP-MS enables accurate, robust, sensitive, and cost-effective routine analysis of trace metal species in a range of matrices.