A new flyer from Thermo Fisher Scientific provides a few examples of how various mass spectrometry techniques can be combined with cryo-EM to provide unique insights beyond protein structures. This includes native MS screening of sample quality prior to vitrification, crosslinking MS to increase the resolution of cryo-electron tomography (cryo-ET) structures, and hydrogendeuterium exchange to provide a dynamic view of static protein structures. Integrative structural biology offers you the solutions to tackle today’s most challenging scientific questions.
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