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Orbitrap_SciLib
Reputable Mentor II
Reputable Mentor II
Angela Criscuolo 1, 2; Tabiwang N. Arrey 2; Eugen Damoc2; Thomas Moehring2; Catharina Crone2 ; Martin Zeller2; Markus Kellmann2
Hupo 2019
Purpose: Structural characterizations of intact monoclonal antibodies by native MS Methods: Size exclusion chromatography and charge variant chromatography were coupled with a Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer. Results: The two methods provided greater depth of analysis of mAbs heterogeneity, showing different benefits respectively.


1 Leipzig University, Leipzig, Germany 2 Thermo Fisher Scientific, Bremen, Germany
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Last update:
‎10-15-2021 09:53 AM
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