Showing results for 
Search instead for 
Did you mean: 

Characterizations of Intact Monoclonal Antibodies by Native MS

Reputable Mentor II
Reputable Mentor II
Angela Criscuolo 1, 2; Tabiwang N. Arrey 2; Eugen Damoc2; Thomas Moehring2; Catharina Crone2 ; Martin Zeller2; Markus Kellmann2
Hupo 2019
Purpose: Structural characterizations of intact monoclonal antibodies by native MS Methods: Size exclusion chromatography and charge variant chromatography were coupled with a Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer. Results: The two methods provided greater depth of analysis of mAbs heterogeneity, showing different benefits respectively.

1 Leipzig University, Leipzig, Germany 2 Thermo Fisher Scientific, Bremen, Germany
Version history
Last update:
‎10-15-2021 09:53 AM
Updated by: