The Nord-Trøndelag Health Study (HUNT) is one of the largest population-based health studies ever performed. Spanning almost 25 years, HUNT now represents an integrated family and personal database of approximately 100,000 people from Nord-Trøndelag County, Norway. Initiated to support epidemiological, clinical and preventative medical research, HUNT offers a valuable insight into disease status and progression, particularly in relation to quality of life measures such as environment, education and occupation. To accommodate for the vast scope of this project, a comprehensive Laboratory Information Management System (LIMS) is required to gather, store, manage, track and retrieve material securely, and be capable of yielding real-time, dependable analysis and reports.