on 05-01-201210:55 AM - edited on 10-15-202111:43 AM by AnalyteGuru
Paschke C, Kellmann M, Xuan Y, Damoc E, Ueckert T, Grensemann H, Comberg U, Delanghe B. Scientific Poster Getting a comprehensive view of the protein content of a complex sample is still a challenge in proteomics; accomplishing it in one analytical run even more so. A lot of efforts have been made the last few years to increase the speed and sensitivity of instruments . Here we describe a combination of a new instrument and data analysis using multiple search engines and proper statistical validation to maximize the number of true positive peptide-spectrum matches (PSMs), distinct peptides and protein groups.