Analysis of Sialylated Glycans with the MALDI LTQ Orbitrap Mass Spectrometer using DHB/N,N-Dimethylaniline Matrix

[steve-day]

The goal of this work is to develop a simple and reliable sample preparation method for the study of sialylated and asialylated glycans by employing DHB/DMA matrix and taking advantage of the high resolving power and mass accuracy of the Thermo Scientific MALDI LTQ Orbitrap XL hybrid mass spectrometer.