Traditionally, the analysis of urine samples has been the major approach for the detecting of drugs of abuse. However, a common risk for this type of analysis is
adulteration or manipulation of the sample at the point of collection. As an alternative, the analysis of oral fluid provides an easy method of sample collection and has the
advantage of providing a relatively clean matrix. Because of the reduced sample volume, this technique requires a high sensitivity and robust analytical method to make an attractive alternative to conventional methods.
United States
