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Analysis of Glycopeptides Using Porous Graphite Chromatography and LTQ Orbitrap XL ETD Hybrid MS

Team TFS
Team TFS
Glycosylation of Asn, Ser or Thr is arguably the most common known post-translational modification (PTM), resulting in a multitude of highly heterogeneous protein isoforms. While the physicochemical differences among the glycosylated protein molecules are often minute, their characterization remains a great analytical challenge. To date, although there are reports of glycoproteome analyses based on electrophoresis techniques, an LC-MS/MS based approach offers advantages in speed, sensitivity, and automation.
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Last update:
‎10-16-2013 07:40 AM
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