This application note demonstrates the analysis by HILIC chromatography of a dextran ladder labeled with a fluorescent tag (2-aminobenzamide). The separation is carried out with a Thermo Scientific™ Accucore ™ 150-Amide-HILIC (150 Å pore diameter solid core) HPLC column. The method is simple, robust and features excellent separations at backpressures compatible with conventional HPLC systems.