The Thermo Scientific™ Acclaim™ AmG C18 column is a high performance silica-based C18 column specifically designed for ion-pairing reversed-phase liquid chromatographic analysis of various aminoglycoside antibiotics, including drug purity and impurity characterization and quantification, therapeutic drug monitoring, and residual control testing in different matrices. The unique column chemistry provides unusual tolerance toward low pH, high temperature, and aqueous mobile phases.