Michalski A, NagarajN, Cox J, Damoc E, Lange O, Wieghaus A, Makarov A, Horning SR, Mann M.
ASMS 2011 Poster
Shotgun proteomics requires mass spectrometric instrumentation with high sequencing speed, sensitivity and resolution. The Orbitrap analyzer provides high resolution in a compact format and is usually combined with a linear ion trap. Here, we instead interface a quadrupole for very fast mass selection to the Orbitrap analzyer and thereby extend the Orbitrap family by a high-performance benchtop instrument.
Max Planck Institute of Biochemistry, Martinsried, Germany.