Zhou Z, Yang M.
ASMS 2015 Poster Note 64417
Purpose: To demonstrate the application of fine isotope pattern filter with ultra high resolution mass spectrometry data for sulfur fumigation abuse monitoring in Traditional Chinese Medicine.
Methods: Sulfur fumigation processed herb powder was analyzed by Thermo Scientific Orbitrap Velos ProTM high resolution mass spectrometer. MS data processing was performed on Thermo ScientificTM Compound DiscovererTM software.
Results: The fine isotope pattern screening method was successfully applied in study of sulfur-fumigated Pueraria species with twelve major sulfur derivatives, eleven of which were tentatively identified according to their HRMSn data which is not known to occur naturally in these samples. The factors which may effect the accuracy of
screening result were also evaluated.
Thermo Fisher Scientific, Shanghai Institute of Materia Medica, Shanghai, China
United States
