Charged aerosol detection has been adopted as the standard technology for COVID-19 vaccine release assays at both Moderna and Pfizer/BioNTech. Check out my blog on a recent application note that describes a simple UHPLC-CAD method for the characterization and quantification of lipid components of LNP formulations.
https://www.analyteguru.com/t5/Blog/Understand-Your-Lipid-Nanoparticle-Composition-with-a-Universal/...
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