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Showing events with label
Mass Spectrometry
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7 attendees
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Introduction to ICP spectroscopy
Monday, April 4, 2022
Join our “Introduction to ICP spectrometry” educational webinar series and learn how to optimize daily routines in your trace e lemental analysis with ICP-OES and ICP-MS . Our experts will demonstrate best practice from sample prep to data evaluation and provide you valuable tips and tricks to simplify and enhance your analytical performance. Register and watch webinar > Webinar agenda: Introduction to ICP spectrometry: Part 1 April 4, 2022 | 10:00 BST | 11:00 CEST Sample Prep – creating serial dilutions from stock standards Sample introduction options and considerations – matrix matching, physical and chemical interferences Inductively Coupled Plasma – RF, plasma effects ICP-OES and ICP-MS cleaning and maintenance Introduction to ICP spectrometry: Part 2 April 5, 2022 | 10:00 BST | 11:00 CEST System Optimization – Performance reports, Mass Cal/Cross Cal, KED interface cleaning, Conditioning Method development – Correct wavelength/viewing mode and isotope selection, interferences – spectral and m/z, determine correct internal standards to use and validation of method Data evaluation – correcting for background and interferences, stability, and sensitivity verification, Examine calibration curves for R2, LOD and saturation, QC data, carryover, and drift correction Can’t attend at these times? Register anyway and automatically receive the recordings to watch at your convenience.
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ICP-MS
ICP-OES
Mass Spectrometry
Optical Emission
Sample Preparation
Webinar
7 attendees
1
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6 attendees
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MSACL
Tuesday, April 5, 2022
Monterey Conference Center, 1 Portola Plaza, Monterey, CA 93940, USA
Thermo Fisher Scientific is a key partner in the success of the clinical mass spectrometry community, as well as a steadfast contributor to MSACL Educational Grants, Scholarships, mentorship programs and the MSACL Connect platform. Check out the technical program for workshops, short courses, and posters! https://lnkd.in/gb9eYTzd April 5-8 Monterey, California https://www.msacl.org/index.php
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Clinical Research
LC-MS
Mass Spectrometry
Orbitrap
Symposium
Trade Show
6 attendees
0
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3 attendees
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Extractables and Leachables USA
Tuesday, April 5, 2022
The Westin Arlington Gateway, 801 North Glebe Road, Arlington, Virginia 22203, United States
At E&L USA Thermo Fisher Scientific will host two plenary talks by experienced E&L scientists. Benton Cartledge, Ph.D. Research Scientist, PPD Laboratory services, will present “Understanding Extractables Profiles Based on the Polymerization Chemistry of Different Materials.” This presentation will focus on butyl rubber, silicone rubber, PET, PBT and polycarbonate. The goal of the presentation will be to provide typical extractables observed from these materials and explain why/how they are formed from the polymerization process. In addition, Chris Shevlin, Scientific and Educational Affairs Manager , Thermo Fisher Scientific, will present “Identification of Polymer Additives Extracted from Single-use Bioreactor Bags.” This workflow has the benefits of sample preparation automation using accelerated solvent extraction and LC HRMS, which can significantly increase sample throughput compared to traditional techniques such as reflux or Soxhlet extraction. Both are trending topics in the field of E&L and should make for fruitful discussions. To learn more about Thermo Fisher's E&L solutions, read this new blog post Thermo Fisher to Present End-to-End E&L Solutions at Extractables & Leachables USA
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Liquid Chromatography
Mass Spectrometry
Pharmaceutical
3 attendees
0
0
1 attendees
2
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Identifying & quantifying MHC antigens with immunopeptidomics webinar
Monday, May 9, 2022
REGISTER HERE Peptides bound to class I major histocompatibility complexes (MHC) play a critical role in immune cell recognition and can trigger an immune response in many disease contexts including cancer, infectious disease, and autoimmunity. The collection of peptide MHCs (pMHCs) present on the cell surface, commonly referred to as the “immunopeptidome,” serves as a rich source of disease-specific targets. Methods to identify the immunopeptidome rely heavily on mass spectrometry to identify thousands of unique pMHC complexes in a relatively unbiased manner. However, analysing MHC MS datasets pose unique challenges over traditional proteomics datasets due to their non-tryptic nature. Here we leverage deep learning via the Thermo Scientific INFERYS Rescoring workflow in Thermo Scientific Proteome Discoverer software to enhance the depth of pMHC identifications from MS analysis, increasing the number of tumor-associated antigens identified in in vitro samples and human tumor specimens. We further apply this analysis framework in conjunction with quantitative immunopeptidomics methods to identify tumor antigens that selectively increase in presentation in response to drug treatment and develop therapeutic strategies to exploit these treatment-modulated antigens as targets for immunotherapy. Learn: • How to use immunopeptidomics to study antigen presentation of MHC molecules • Understand how artificial intelligence helps dig deeper into immunopeptidomics mass spectrometry data to identify tumor antigens • Understand how implementing quantitative mass spectrometry-based approaches can identify treatment-modulated tumor antigens as targets for immunotherapy REGISTER HERE Speaker: Dr. Lauren Stopfer Lauren earned a B.S. from the University of Wisconsin-Madison and Ph.D. from the Massachusetts Institute of Technology studying phosphoproteomics, immunopeptidomics, and systems biology. She is currently a scientist on the Proteomics team at BioNTech US, where she focuses on applying proteomics and immunopeptidomics methodologies to oncology and infectious disease applications.
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LC-MS
Mass Spectrometry
Proteomics
1 attendees
2
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1 attendees
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Elucidating the effects of substrate availability on growth and utilization in pathogenic microbes
Tuesday, May 17, 2022
A sub-class of pathogenic microbes exhibit drastically increased biomass accumulation when supplemented with SCFAs. This phenomenon was probed via stable isotope resolved untargeted metabolomics leveraging Thermo Scientific™ Compound Discoverer™ software. Metabolites presenting fold changes as well as downstream isotopic enrichment from a 13 C 2 acetate substrate were used to inform on this unusual phenomenon and increase our understanding of the microbe's pathogenic mechanism. Learn: Understand how to study biological metabolism with liquid chromatography-mass spectrometry Learn how to perform untargeted stable isotope labeling experiments See advanced tools for analyzing and reporting untargeted stable isotope labeling data REGISTER HERE
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Mass Spectrometry
Metabolomics
Webinar
1 attendees
0
0
1 attendees
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Toward A Next-Generation MAM: An Evaluation of the Orbitrap Exploris MX Mass Detector Webinar
Wednesday, May 25, 2022
In the development of biotherapeutics, a thorough understanding of a molecule’s product quality attributes (PQAs), and their effect on various structure-function relationships and long-term stability, is essential for ensuring the safety and efficacy of the product. At present, numerous routine chromatographic and electrophoretic assays are used to characterize and monitor individual PQAs. However, execution of multiple routine methods for batch release, stability time-points, and process/formulation development support becomes time and resource intensive, and often provides an indirect measure of biologically relevant PQAs. Introduced in 2015, the multi-attribute method (MAM), based on LC-MS peptide mapping and automation principles, provides simultaneous and site-specific detection, identification, quantitation, and quality control (monitoring) of PQAs. A dedicated Pfizer team has been regularly employing MAM on an in-house MAM platform to support biotherapeutic process and product development. In parallel, this team has continually explored and implemented improvements in the Pfizer MAM platform, including sample preparation and data processing automation, to move toward the next generation of MAM. Recently, a pre-commercial demo model of the new Thermo Scientific Orbitrap Exploris MX mass detector was evaluated in-house by the Pfizer MAM team. Here, the results of the evaluation and an assessment of the Orbitrap Exploris MX mass detector’s suitability as a next generation MAM instrument are presented. Learn: Pfizer MAM platform milestones for characterization and routine monitoring Automation of sample handling and data processing and reporting Evaluation and optimization of the Orbitrap Exploris MX mass detector for MAM REGISTER HERE
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Biopharmaceutical
Chromatography Data System Software
LC-MS
Mass Spectrometry
Webinar
1 attendees
0
0
3 attendees
0
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70th ASMS Conference on Mass Spectrometry and Allied Topics
Sunday, June 5, 2022
Minneapolis Convention Center, 2nd Avenue South, Minneapolis, MN, USA
Join us at the annual conference of the American Society for Mass Spectrometry in Minneapolis, MN. Please revisit this page for additional information. At this year’s ASMS learn about the latest innovations that scale the molecular spectrum. From targeted and small molecule quantitation, through advancements in high throughput quantitative proteomics and bio-molecular characterization, to a revolution in intuitive, AI-driven software for leading-edge biological research. Our experts and collaborative partners will be onsite all week in Booth 400, so be sure to stop by. We look forward to seeing and partnering with you at ASMS 2022. Register to attend our lineup of Users' meetings, Breakfast workshops and Customer Hospitality event at ASMS 2022. Register Here For more information
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Conference
GC-MS
Mass Spectrometry
3 attendees
0
0
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