Showing results for 
Search instead for 
Did you mean: 

Host Cell Protein (HCP) Profiling & Quantitation in Gene Therapy Products with Orbitrap Astral MS

Published on ‎09-20-2023 09:39 AM by Team TFS | Updated on ‎09-20-2023 09:40 AM

an-000253-lsms-aav-capsid-proteins-an000253 1080 w.jpg

Live Webinar: Host Cell Protein (HCP) Profiling and Quantitation in Gene Therapy Products with the Orbitrap Astral Mass Spectrometer

Wednesday, September 27, 2023

10:00 am PT, 1:00 pm ET, 19:00 CET




Live webinar featuring an overview of Host cell protein (HCP) profiling and quantitation in gene therapy products on a novel high-resolution accurate mass platform.   Learn how you can achieve confident, sensitive and reproducible AAVHCP identification and sub-ppm quantification using a novel HRAM platform with increased throughput.


This webinar will demonstrate approaches to over come key challenges with AAV HCP analysis, such as the highly complex proteome background and large dynamic range which necessitate the need for high sensitivity enabling the detection and quantification of low abundant HCPs, essential for safe and efficacious production of these advanced biotherapeutics.


In this webinar you’ll learn:

  • How to overcome challenges in HCP analysis of AAV based gene therapies 
  • How to ensure you accurately profile and quantify critical HCP contaminants in the sub ppm range 
  • How the new Thermo ScientificTM OrbitrapTM AstralTM Mass Spectrometer can aid your HCP analysis

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelist.




Jonathan Bones, Ph.D.

Principal Investigator
Characterization and Comparability Group



Kai Scheffler, Ph.D.

Senior Manager, Product Management - Workflows
Thermo Fisher Scientific



Wed, Sep 27, 2023 10:00 AM PDT
Wed, Sep 27, 2023 11:00 AM PDT