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Elucidating the effects of substrate availability on growth and utilization in pathogenic microbes w

Published on ‎04-21-2022 04:49 PM by Team TFS | Updated on ‎05-17-2022 07:04 AM

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A sub-class of pathogenic microbes exhibit drastically increased biomass accumulation when supplemented with SCFAs. This phenomenon was probed via stable isotope resolved untargeted metabolomics leveraging Thermo Scientific™ Compound Discoverer™ software. Metabolites presenting fold changes as well as downstream isotopic enrichment from a 13C2 acetate substrate were used to inform on this unusual phenomenon and increase our understanding of the microbe's pathogenic mechanism.



  • Understand how to study biological metabolism with liquid chromatography-mass spectrometry
  • Learn how to perform untargeted stable isotope labeling experiments
  • See advanced tools for analyzing and reporting untargeted stable isotope labeling data


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Tue, May 17, 2022 08:00 AM PDT
Tue, May 17, 2022 09:00 AM PDT
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