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Problem with GC-IRMS

Hi,I am a Ph.D. student. I am working with GC-IRMS. We have MAT 253 IRMS along with Ultra trace GC. and GC interfaced with IRMS through GC combustion III.Recently I had a problem of really high water background after doing maintenance e.g. changing t...

Full Scan and PRM for quantification

Hi everyone, I would like some clarifications regarding the PRM technique. I have always used this technique for the Orbirtrap Q Exactive Focus for quantification analyzes on food matrices. By doing some tests on a matrix, I realize that the full sca...

method of dosed additions

Hello,I am using a GC-Orbitrap for quantitative analysis.I am doing the method of dosed additions but the software is hard to use with this method.I know that with tracefinder for the standard dosed additions method, there is no need to inject the un...

Orbitrap Calibration issue

Hi,We have an Orbitrap Velos mass spectrometer. We are having trouble calibrating the same, and the data we get is inaccurate. The spray seems to be stable. I have tried cleaning the ion transfer tube, changing LC solvents, and using a new Calmix. Al...

RawFileReader reading of audit trial in raw files

Hello, I have an export of cmbx file which contains a raw files. I am unable to read the audit trial information from the raw files. Can someone please guide. For example if there is 1 injection within a sequence and I export in chromeleon to cmbx fi...

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