Orbitrap Calibration issue

[gpandey]

Hi,
We have an Orbitrap Velos mass spectrometer. We are having trouble calibrating the same, and the data we get is inaccurate. The spray seems to be stable. I have tried cleaning the ion transfer tube, changing LC solvents, and using a new Calmix. All the tests pass except for 'Positive Ion Multiplier Gain Calibration.' I would really appreciate any help in this regard.

Thanks,
Gaurav