Blog
Your educational resource for the latest applications, information and research in sample preparation, chromatography, mass spectrometry, trace elemental analysis and laboratory data management.
cancel
Showing results for 
Search instead for 
Did you mean: 

Blog Articles

Don’t Get Lost in Your HPLC Method Development

HPLC method development is a bit like trying to solve a maze. The goal – the cheese, if you will – is to develop a method that provides adequate resolution, sensitivity, robustness and throughput. Sou...

0 Comments

How Liquid Chromatography Benefits the Planet

PSA: Climate change is real!Melting glaciers and the extinction of polar bears. Dead coral reefs and acidification of the ocean. Increased droughts and raging wildfires. A warming ocean and stronger h...

0 Comments

Are You Missing Analytes in Your Liquid Chromatography?

I’m sure that is a question that many cannot answer. How do you know if you are missing analytes if you’ve never detected them previously? I am confident, though, that most would wish to have the conf...

0 Comments

The Role of HPLC in Metabolomics

Mass spectrometry-based metabolomics is frequently coupled to a diverse range of chromatographic techniques such as liquid chromatography (LC), ion chromatography (IC), and gas chromatography (GC).I r...

0 Comments

Why Your Lab Should Upgrade Its HPLC or UHPLC System

Making the switch isn’t always easy, but it’s worth the investment. I vividly remember the day in graduate school when my advisor asked me if I’d be “okay” giving up the HPLC instrument I used for two...

0 Comments

The What, Why, and How of Productivity in Your HPLC Lab

In the mid-1970s, the combination of industrial action by coal miners with the OAPEC oil embargo meant that the UK was running desperately short of fuel for electricity generation. As a result, the go...

0 Comments

The Finite Lab

We all accept that modern research life requires us to balance creativity with maximizing the return on investment of our instrumentation. In fact, both these demands continue to grow, and at a certai...

0 Comments

HPLC or UHPLC?

This almost sounds like a line from Shakespeare, but HPLC or high-performance liquid chromatography and ultra-high-performance liquid chromatography (UHPLC) came a little after the ‘Bard of Avon.’ Bot...

0 Comments

How to Stop Your Mass Spectrometer Procrastination

If 10 years ago you told me I would be writing an article about avoiding procrastination I would have laughed as I thought I was a procrastinator myself. I have come to realise that it wasn’t ‘true’ p...

0 Comments

Five Additional Pharmaceutical Impurity Questions

Over the past two months, and during our recent pharmaceutical impurity workshop in Switzerland with LGC Standards, we’ve been asked some additional questions related to pharmaceutical impurities. In ...

0 Comments

What Is Dual LC and How Does It Benefit Me?

I think we can all generally agree that usually two is better than one: a bicycle is more efficient than a unicycle, two hands or minds are often better than one at completing tasks, etc. Does this tr...

1 Comments

Top Four Questions about Pharmaceutical Impurities

Over the past year, myself and Dr. Christian Zeine of LGC, have been engaging with scientists involved in the analysis of pharmaceutical impurities. During this time, there have been some questions th...

2 Comments

Six Glycan Analysis Strategies for Biotherapeutics

Glycosylation is one of the most common protein post-translational modifications and can affect the protein’s functionality, stability and immunogenicity. It is for these reasons that for biopharmaceu...

0 Comments

Detector Technologies for (U)HPLC

When it comes to liquid chromatography there are numerous choices available for the detection of your analyte, but which of these offers the greatest sensitivity, is most suitable for your particular ...

0 Comments

The Jumbo Jet and HPLC Instruments

You may read the title of this article and wonder how these two are connected as they seem about as far apart as you could possibly imagine. But there are more similarities than you think. And, I beli...

0 Comments

Trends in Biopharmaceutical Characterisation

I’m writing this article following a day at NIBRT (National Institute for Bioprocessing Research and Training) in Dublin, Ireland attending the Thermo Fisher Scientific Biopharma Summit. NIBRT and The...

2 Comments

How Viper Changed My Life

Some years ago I was a young university researcher having fun developing new LC-MS methods. I worked with passion and enthusiasm and did the best I could with my LC instruments, but I always avoided U...

0 Comments