The Twelve Days of Ion Chromatography (IC)
Sing along to "The 12 Days of Christmas" On the first day of Christmas my IC expert sent to me: One eluent water polisher On the second day of Christmas my IC expert sent to me: Two EGCs (eluent gener...
Blog Articles
Festive Deals for Your Chromatography Consumables
Did someone say Christmas? Aside from presents, delicious food and fairy lights, why not treat your lab with all your chromatography essentials for a great price ahead of the new year? Our big end-of-...
Feeling Sample Prep Burnout? Let Your GC Autosampler Help With Your Workload
Gas chromatographers know how much of their time performing analytical work is taken up preparing samples for the injection. Most of the GC analysis time often involves several manual handling procedu...
Why Is Sample Preparation Such a Major Headache in Food Analysis?
Sample matrix There are as many sample preparation options available as there are matrices. Some are more regulated than others, but it all starts by looking at the matrix under consideration.A highly...
Automating Sample Preparation for Food Analysis – the Holy Grail!
Why is this the holy grail? We all know food samples are tricky. There are a lot of different matrices, analytes, contaminants and sample preparation methods to consider in food analysis, making this ...
Is Automating Sample Preparation Just About Convenience?
Almost every modern-day method uses recent technology in instrumentation for the detection and quantification of whatever analyte or analytes are of interest. The benefits of today’s systems are very ...
When Smoky Wines Don’t Taste Good!
Many people like a certain flavor of smokiness in food and alcoholic beverages, and certain types of wines aged in toasted oak barrels are appreciated for their smoky notes. However, the sensation is ...
The Chemistry of Winemaking: How SPME Can Help
“Wine is one of the most civilized things in the world and one of the most natural things of the world that has been brought to the greatest perfection, and it offers a greater range for enjoyment and...
Thermo Scientific™ Dionex™ Ion Chromatography (IC) – A Precision Instrument
For more than 45 years, Thermo Scientific™ Dionex™ IC systems have enabled extraordinary breakthroughs and discoveries in applied and life sciences. IC is a physical-chemical separation method, which ...
Workflow for the Detection of Fentanyl and nor-Fentanyl Down to 0.1 Ng/Ml in Urine After Fentanyl Skin Patch Abuse
One form of Fentanyl therapy is the use of skin patches.Over the past few years, it has been found that Fentanyl abusers will chew used skin patches – which can still contain 70% of the Fentanyl -- th...
Something Big Is Going to Happen
Do you ever daydream about a surprise birthday party your lab colleagues might organise for you? A secret party that you are completely oblivious to and don’t even notice the subtle hints of confetti ...
Match the Goals of Automated Sample Prep for GC Analysis
In a previous blog post, I commented on the opportunity to use modern robotic technology to make our life easier by automating low-value routine activities. Doesn’t matter if it is for housekeeping du...
Micro SPE Providing Mighty Productivity in Pesticides Analysis
The Pesticides Analytical Challenge Laboratories involved in pesticide residue analysis in foods are often challenged to analyse hundreds of different pesticides in hundreds of different sample types ...
Automate Sample Preparation for PFAS Analysis in Drinking Water
Now you can automate sample preparation for the analysis of per- and polyfluoroalkyl substances (PFAS) in drinking water by EPA method 537.1 and method 533. We are all in the market to support laborat...
The Day the Clinical Trial Stood Still
Well over a decade ago I was sitting in a weekly project meeting, eagerly awaiting my workload for the week. I was a keen bioananalyst, only a couple of years into my role, learning to produce good qu...
Pittcon 2019 – Day 2 – Advanced Chromatography Preparation and Separation Solutions Deliver Robust and Reliable Sample Analysis
It’s the second day on the show floor at Pittcon 2019 and the fun is just beginning. Today’s standout solution is the Thermo Scientific SMART Automation workflow.Laboratories can access advanced analy...
Pittcon 2019 – Day 1 – New Automated Sampling Solution for Volatile Organic Compounds Analysis
It’s day one at Pittcon 2018 in Philadelphia! Thermo Fisher Scientific has some exciting announcements this week, so be sure to check in each day to see what’s happening. If you’re at the show, be sur...
Rapid, Automated Peptide Mapping for Multi Attribute Monitoring
Peptide mapping is a fundamental workflow required to ensure bio-therapeutics structural integrity is maintained at all stages of the drug development pipeline. This is required for maintenance of dru...
Building Immunity with the Right Tools
Worldwide, researchers are searching for ways to boost the immune system’s ability to fight cancer; one such way is by developing novel therapeutics within the pharmaceutical/biopharmaceutical industr...
How to Improve Your ICP-MS Analysis, Part 3: Sample Preparation and Handling
In part 1 of this series, I covered the issues of contamination and sample-to-sample memory effects in ICP-MS and how you can solve them. In part 2, I moved on to the challenge of interferences and ho...
Rapid Automated Peptide Mapping
The growth of bio–therapeutics has occurred mainly due to the greater success rates within the clinical trials phase of drug development. This means that more drugs are being brought to market. Due to...
Synthetic Urine, A Clean Catch?
With the opioid crisis raging and recreational marijuana use becoming legal in nine US states and the District of Colombia, the concerns about clean drug tests are on the rise. While urine remains the...
GC-MS Can Tell If You Are a Choc-a-holic
Recently we had the opportunity to collaborate with a major lab in Germany that specializes in analyzing urines for drugs of abuse. The lead pharmacist there showed me her lab and explained in detail ...
Shooting Daggers at Liquid Sample Preparation for GC and GCMS Analysis with SPME Arrow
When working in a lab with a GC or GCMS system you quickly realize that sample preparation takes a lot of time. Unlike LC or LCMS we simply cannot inject water…well we can, but only a tiny amount at o...
When You Start Dreading the Weekend
It’s that dreaded time of the year where I start to NOT look forward to weekends. Given that it is the only time I have to do my taxes, I’m sure you understand why. I can usually fight through reading...
BioPharMoore: Unravelling Biopharmaceutical Protein Digestion
Early in the development stages of any protein therapeutic, a peptide mapping experiment is undertaken. A peptide map involves breaking the macromolecular protein structure down into its constituent p...
What’s faster? Digesting a protein, or reading this blog?
When it comes to biotherapeutic protein digestion for peptide mapping or large molecule bioanalysis you’ve got a terribly difficult choice: Lengthy, cumbersome and error prone in-solution digestion, O...
Can Protein Digestion Really Be 3 Simple Steps?
Until recently we used a 2-day protocol to characterize proteins, but now with the new immobilized trypsin kit we’re down to 1 hour for large protein such as Immunoglobulin G (IgG).Find out more and w...
Not All Who Wander Are Lost
Since I can remember I’ve always had a thing about collecting maps. I have folders full of free ones detailing places from childhood holidays, road atlases covering a large proportion of the globe, ol...
RoboTop: Automated Sample Preparation for GC and GC-MS
Why are the robots in Hollywood movies often depicted as evil? I am guessing it must be because most of the time they are pointing out our own shortcomings as humans and therefore we feel much more co...
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