Sample matrix There are as many sample preparation options available as there are matrices. Some are more regulated than others, but it all starts by looking at the matrix under consideration.A highly...
Why is this the holy grail?We all know food samples are tricky. There are a lot of different matrices, analytes, contaminants and sample preparation methods to consider in food analysis, making this f...
Almost every modern-day method uses recent technology in instrumentation for the detection and quantification of whatever analyte or analytes are of interest. The benefits of today’s systems are very ...
Many people like a certain flavor of smokiness in food and alcoholic beverages, and certain types of wines aged in toasted oak barrels are appreciated for their smoky notes. However, the sensation is ...
“Wine is one of the most civilized things in the world and one of the most natural things of the world that has been brought to the greatest perfection, and it offers a greater range for enjoyment and...
For more than 45 years, Thermo Scientific™ Dionex™ IC systems have enabled extraordinary breakthroughs and discoveries in applied and life sciences. IC is a physical-chemical separation method, which ...
One form of Fentanyl therapy is the use of skin patches.Over the past few years, it has been found that Fentanyl abusers will chew used skin patches – which can still contain 70% of the Fentanyl -- th...
Do you ever daydream about a surprise birthday party your lab colleagues might organise for you? A secret party that you are completely oblivious to and don’t even notice the subtle hints of confetti ...
In a previous blog post, I commented on the opportunity to use modern robotic technology to make our life easier by automating low-value routine activities. Doesn’t matter if it is for housekeeping du...
The Pesticides Analytical Challenge Laboratories involved in pesticide residue analysis in foods are often challenged to analyse hundreds of different pesticides in hundreds of different sample types ...
Now you can automate sample preparation for the analysis of per- and polyfluoroalkyl substances (PFAS) in drinking water by EPA method 537.1 and method 533. We are all in the market to support laborat...
Well over a decade ago I was sitting in a weekly project meeting, eagerly awaiting my workload for the week. I was a keen bioananalyst, only a couple of years into my role, learning to produce good qu...
It’s the second day on the show floor at Pittcon 2019 and the fun is just beginning. Today’s standout solution is the Thermo Scientific SMART Automation workflow.Laboratories can access advanced analy...
It’s day one at Pittcon 2018 in Philadelphia! Thermo Fisher Scientific has some exciting announcements this week, so be sure to check in each day to see what’s happening. If you’re at the show, be sur...
Peptide mapping is a fundamental workflow required to ensure bio-therapeutics structural integrity is maintained at all stages of the drug development pipeline. This is required for maintenance of dru...
Worldwide, researchers are searching for ways to boost the immune system’s ability to fight cancer; one such way is by developing novel therapeutics within the pharmaceutical/biopharmaceutical industr...
In part 1 of this series, I covered the issues of contamination and sample-to-sample memory effects in ICP-MS and how you can solve them. In part 2, I moved on to the challenge of interferences and ho...
The growth of bio–therapeutics has occurred mainly due to the greater success rates within the clinical trials phase of drug development. This means that more drugs are being brought to market. Due to...
With the opioid crisis raging and recreational marijuana use becoming legal in nine US states and the District of Colombia, the concerns about clean drug tests are on the rise. While urine remains the...
Recently we had the opportunity to collaborate with a major lab in Germany that specializes in analyzing urines for drugs of abuse. The lead pharmacist there showed me her lab and explained in detail ...
When working in a lab with a GC or GCMS system you quickly realize that sample preparation takes a lot of time. Unlike LC or LCMS we simply cannot inject water…well we can, but only a tiny amount at o...
It’s that dreaded time of the year where I start to NOT look forward to weekends. Given that it is the only time I have to do my taxes, I’m sure you understand why. I can usually fight through reading...
Early in the development stages of any protein therapeutic, a peptide mapping experiment is undertaken. A peptide map involves breaking the macromolecular protein structure down into its constituent p...
When it comes to biotherapeutic protein digestion for peptide mapping or large molecule bioanalysis you’ve got a terribly difficult choice: Lengthy, cumbersome and error prone in-solution digestion, O...
Until recently we used a 2-day protocol to characterize proteins, but now with the new immobilized trypsin kit we’re down to 1 hour for large protein such as Immunoglobulin G (IgG).Find out more and w...
Since I can remember I’ve always had a thing about collecting maps. I have folders full of free ones detailing places from childhood holidays, road atlases covering a large proportion of the globe, ol...
Why are the robots in Hollywood movies often depicted as evil? I am guessing it must be because most of the time they are pointing out our own shortcomings as humans and therefore we feel much more co...
Ever given someone a blank stare when you don’t understand what they are saying? Just last week, a very uninteresting Auto Center employee was rattling off a bunch of convoluted, technical terms to ex...
Talking about ghosts, zombies, and witchcraft is enormously popular these days, and we are chiming in on the hype today by talking about ghost peaks in GC and GC-MS.We thought we could get away with i...
This morning I popped a piece of bread in the toaster, planning to spread butter and jam on it then drink it with my coffee. But I left the toast in the toaster too long, and it came out charred and b...
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