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Blog Articles

What Makes an HPLC Column?

September 2021 saw the launch of a new low-flow UHPLC solution, the Thermo Scientific™ Vanquish™ Neo UHPLC system and Thermo Scientific™ PepMap™ Neo UHPLC columns. When we talk about HPLC columns, ter...

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Proteomic Sample Multiplexing Comes of Age

For a young person, turning 18 is a big milestone. In most countries, this is the age when you are legally recognized as an adult, able to vote in elections and are eligible for military service. For ...

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Next-Generation Low-Flow LC Technology is Not Marketing Buzz

What does it mean to be the next generation? You don’t have to look far to find the term “next-generation” or “NextGen” used to describe new technology. But what does it mean to describe a product or ...

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Virtual 2020

As 2020 draws to a close it is a good time to reflect on what has probably been the strangest year that most of us have ever experienced. The word ‘unprecedented’ has been worn out by overuse and the ...

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How Not to Waste an Entire Day – Even in Research

Recently, I was applying for a visa to visit India. I had two options – either I walk my application into the San Francisco Indian Embassy or I could mail in my application and my passport. The number...

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Personalized Medicine Quick Guide

The term personalized medicine has been used for many years, I can certainly remember it being a buzz word when I started my research career at the start of the century, and it has been practiced in a...

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Admiring the Architecture of the Building Blocks of Life

After almost a decade of studying and analysing proteins I’ve often found myself trying to explain to people “Why proteins?” What’s all the fuss about?I recently came across this video produced for th...

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The Meaning of Life

I have heard and read many definitions of what life is, what it means, what it means to lead a good life, etc. I am really not sure that ‘What is the meaning of life?’ is itself a meaningful question....

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The Social Network of Cellular Biology

Understanding the molecular sociology of proteinsAt some point during our education most of us learn some basic cell biology with cartoons of cells and organelles in text books, illustrating cellular ...

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Systems-Wide Proteomics Comes of Age

Is systems-level proteomics ready for a seat at the table with our genomics colleagues, as a full partner contributing to large-scale biological research, translational research and personalized medic...

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Precision Medicine… Precisely

Change is coming. Precise change.2015 was a very interesting year: Human gene editing with CRISPR-Cas9 (the ethics of which are very much being debated), effective immunotherapy, two promising vaccine...

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A Brief History of and Guide to Peptide Mapping

I finished my PhD and began my career as an R&D scientist at the start of the millennium, when proteomics was in its infancy. In those days, peptide mapping was all the rage as researchers looked to b...

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The Promise of Proteogenomics: Precision Medicine

Proteogenomics, the integration of proteomics with genomics, is an emerging approach that promises to advance clinical & translational research. By combining genomic and proteomic information, leading...

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Why I Turned from Phosphorylation to Glycan Analysis

Most of my early research career focused on the post-translational modifications (PTMs) of proteins and in those days there was only one worthy PTM in my eyes and that was phosphorylation while glycos...

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