After 20 years of working in the pharmaceutical industry scouting active drugs in research to take to market, along with method transfer to the manufacturing site, I have learned that there is no such...
Tromethamine is a useful compound in pharmaceutical formulations acting as a buffering agent, an alkalizer, an emulsifying agent, or a counterion for acidic drug substances. Although tromethamine brin...
Don’t miss your opportunity to join thought leaders and industry experts in three upcoming pharma-focused events. We will kick things off with a webinar focused on the real impact of HPLC. We will the...
Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) are important inactive components to improve over-the-counter (OTC) pharmaceutical formulations. Compounds in this fa...
Modern advances in pharmacology have resulted in positive benefits for patients fighting disease, including increased life expectancy and reduced suffering from disease symptoms. Many of us, our famil...
Why is the 5’ capping important? The 5’ cap of mRNA plays multiple key biological functions: regulation of nuclear export, prevention of degradation by exonucleases, and promotion of translation. To e...
It was springtime this year when the new Thermo Scientific GC and GC-MS product portfolio was announced during an exciting Innovation Summit virtual event. A series of interesting presentations touchi...
The sun shone down on Cambridge as we saw a welcome return of the International Reid Bioanalytical Forum. The event had been rescheduled several times from its normal slot in September and was now nes...
For the first time ever, proteomics and biopharmaceutical laboratories working in drug discovery and R&D applications can unlock the ability to clearly decipher complex mixtures of large molecules wit...
AnalyteGuru continues its Networking in Science webinar series with Naiffer Romero, Senior Scientific Affairs Manager, MSc, MPH, United States Pharmacopeia (USP), on May 24 at 10 a.m. CDT. In this web...
Discussing industry-wide challenges among industry peers is the best way to share information and take key learnings from the experiences of others. We all live and work in the same set of evolving re...
N-nitrosodimethylamine (NDMA) is a highly hepatotoxic compound and known carcinogen. In recent years, several drugs, including losartan, ranitidine, and metformin, have been recalled by the U.S. Food ...
AnalyteGuru continues its Networking in Science webinar series with Paulina Pinedo-Gonzalez, Ph.D., from SGS, Fairfield, New Jersey, on May 11 at 10 a.m. CDT. In this webinar, Dr. Pinedo-Gonzalez will...
The Chromatography & Mass Spectrometry Division and the Clinical Research Business (which includes PPD® Laboratory services) of Thermo Fisher Scientific will host side-by-side booths and conference ta...
Magnesium is the fourth most abundant cation in the human body and plays a key role in many physiological processes, including regulating nerve and muscle function and supporting energy production. To...
This month the European Medicines Agency (EMA) issued further revisions to the ever-changing guidance for drug producers when it comes to nitrosamine testing. In 2018 the Federal Drug Administration (...
While ASMS 2021 in Philadelphia is coming to a close, there are no shortages of announcements coming from a busy week filled with innovations and solutions for scientists in proteomics, biopharmaceuti...
The week is flying by at ASMS 2021 in Philadelphia and the latest innovations continue to roll out for biopharmaceutical laboratories working across R&D, manufacturing and quality control (QC) environ...
ASMS 2021 is fully underway in Philadelphia, PA and once again we are excited to be empowering scientists to drive groundbreaking discoveries with the introduction of new-generation mass spectrometry ...
For years, laboratory professionals gained knowledge through hands-on experience, personal interactions and discussions at forums, symposiums, workshops and seminars. Not much had changed since I emba...
Curiosity is the primary driver of science. But developing natural curiosity into scientific thinking and motivation to uncover the endless wonders of nature is a difficult task. The Information Techn...
Cyclodextrins are an important family of pharmaceutical excipients that are widely used as complexing agents to increase the aqueous solubility of poorly water-soluble drugs. With their characteristic...
Zinc oxide is an important active ingredient in sunscreen, providing protection from potentially damaging ultraviolet (UV) radiation by scattering, reflecting and absorbing sunlight. Zinc oxide is uni...
The use of performance-enhancing anabolic substances has been banned since the 1970s in competitive sports. However, substances, especially steroids, are still frequently detected and misused in sport...
It was Pittcon 2019 when the Thermo Scientific™ TriPlus 500 Headspace Autosampler was introduced to the market of volatiles organic compounds (VOC) sampling for GC and GC-MS. Thermo Scientific TriPlus...
Like everyone, I have been relieved to see the end of a challenging year. It is easy to look back on 2020 and be sad for the many things we missed out on. No doubt we still have challenges ahead, but ...
In Part 1 and Part 2 of this blog series, we touched upon ways ion chromatography (IC) can have more uses in the pharma lab than just for counterion analysis and how it offers a direct approach to pol...
In my last blog post, “Challenging pharmaceutical impurity analyses Part 1 – Derivatization – first choice or last resort?” I looked into some of the issues that could occur when using derivatization....
With pharmaceutical impurities under increasing scrutiny, recently so with the nitrosamine issues in Ranitidine and prior to that Valsartan, the question of ‘What’s in our medicines?’ has never been m...
This diary belongs to Tom, I’m married with two small children aged 5 and 7 and work in the QA/QC department of a medium-sized pharmaceutical company in the UK. This year, I’ve decided to keep a diary...
stephaniekoczur
on:
Celebrating International Women's Day: A Tribute t...
klincoln
on:
How Much Microplastic Do You Eat in a Day?
MDykstra2021
on:
Let’s Have the Talk, the Procurement Talk
Anna_Blank
on:
Analyzing Trace Oxyhalides, Inorganic Anions in Dr...
The_Ion_Lady
on:
Celebrate the Science Behind the Food on National ...
klincoln
on:
The Top 10 AnalyteGuru Blog Posts of 2022
TC_IC-fun
on:
The Twelve Days of Ion Chromatography (IC)
The_Ion_Lady
on:
Simplifying Sugar Determination in Food With HPAE-...
GeorgeTFS
on:
What Did Thermo Fisher Scientific Have To Do With ...
MattDoig
on:
Efficiency Using CDS, LIMS: On-Demand Presentation...
United States
