Peptide mapping is a fundamental workflow required to ensure bio-therapeutics structural integrity is maintained at all stages of the drug development pipeline. This is required for maintenance of dru...
As 2018 draws to a close, it’s been another exciting year in the area of biopharmaceuticals. We’ve seen further success from immunotherapy based approaches, new biopharmaceuticals have come to market ...
Synthetic oligonucleotides and peptides are frequently used in both research and medicinal applications today. Their synthesis is relatively straightforward, but they undergo quality control to confir...
If you review any charts of the top 10-20 selling drugs over the past decade you will quickly notice that drugs based on monoclonal antibodies are now overtaking their small molecule alternatives and ...
I’m writing this article following a day at NIBRT (National Institute for Bioprocessing Research and Training) in Dublin, Ireland attending the Thermo Fisher Scientific Biopharma Summit. NIBRT and The...
Being the youngest and only girl in the family has meant that I’ve provided my dad with that little extra level of worry. My dad is a cautious soul; especially when it comes to his children and their ...
I’d like to start off with one powerful example of why immunotherapy work is so important. The story comes from Ron Levy’s work to use antibodies to fight lymphoma. One moving case describes a 36 year...
When it comes to biotherapeutic protein digestion for peptide mapping or large molecule bioanalysis you’ve got a terribly difficult choice: Lengthy, cumbersome and error prone in-solution digestion, O...
On a rainy winter’s day in Boston, MA, we took a journey in biotherapeutic peptide mapping with Guilong Charles Cheng of Alexion Pharmaceuticals, Inc. Join us on this journey and discover how advancem...
Until recently we used a 2-day protocol to characterize proteins, but now with the new immobilized trypsin kit we’re down to 1 hour for large protein such as Immunoglobulin G (IgG).Find out more and w...
Since I can remember I’ve always had a thing about collecting maps. I have folders full of free ones detailing places from childhood holidays, road atlases covering a large proportion of the globe, ol...
I finished my PhD and began my career as an R&D scientist at the start of the millennium, when proteomics was in its infancy. In those days, peptide mapping was all the rage as researchers looked to b...
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