Top 10 AnalyteGuru Blog Posts of 2021
As we close out 2021, the team at AnalyteGuru would like to wish you a safe and happy holiday season. It was an eventful year for us. We grew our analytical science blog into a scientific community, a...
Blog Articles
How the New Orbitrap Exploris GC-MS Can Help Enhance Quantitative Performance for Analytical Testing Laboratories
In high-throughput analytical testing laboratories robust streamlined analytical and data processing workflows are key requirements for the accurate and reliable determination of trace level residues ...
Discover the Next Generation High-Resolution GC-MS: Orbitrap Exploris GC and Orbitrap Exploris GC 240
[caption id="attachment_22778" align="alignright" width="1020"] Orbitrap Exploris GC 240[/caption]Although the technological principles that underlay its conception date back to 1923, when Kingdon fir...
Integrative Structural Biology and Its Moment in the Spotlight
If we needed evidence that virus research is an important area to focus on, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and cumulative COVID-19 human health impact have p...
Mass Spec Goes Mainstream
High-performance biopharmaceutical characterization for everyone!I’ve just recently celebrated five years in my current role here at Thermo Fisher Scientific. Wow, where did those years go? I love wha...
Discover Deeper Insights Into Your Sample
In my last blog post, “Looking for Certainty,” I took a closer look at the importance of data certainty and how it’s critical to all applications, but especially in contaminant testing. The importance...
Looking for Certainty
It’s a very uncertain world. Who knows what the future holds? If anything is certain, it’s that 2020 is not the year we all thought it was going to be. Having certainty is important in everything we d...
Workflow for the Detection of Fentanyl and nor-Fentanyl Down to 0.1 Ng/Ml in Urine After Fentanyl Skin Patch Abuse
One form of Fentanyl therapy is the use of skin patches.Over the past few years, it has been found that Fentanyl abusers will chew used skin patches – which can still contain 70% of the Fentanyl -- th...
Breath Biopsy™ – How Exhaled Breath Can Be Used to Uncover Disease and Cancer
Biomarker studies using exhaled breath are rapidly emerging as a novel approach for early disease detection and precision medicine. In my last blog article - Breath Biopsy™ – A Non-invasive Tool for t...
Penguins, POPs and Pandemic
Like Batman and Robin, or Han Solo and Chewbacca, combining gas chromatography with Orbitrap technology was always going to be a winning combination. With needle-sharp chromatographic peaks and high m...
Sports Doping – How Isotopes Help to Fight the Crime (Part 2)
Performance-enhancing drugs are substances that have the capability to improve performance in humans. In sports, those substances are sometimes referred to endogenic aids and one highly popular refere...
Breath Biopsy™ – A Non-invasive Tool for the Early Detection of Disease and Cancer
Research Use Only, Not for Diagnostic ProceduresWhen you think of diagnostic tests for disease and cancer, the first that probably come to mind rely on using samples of blood or tissue. While these me...
Enabling Testing Laboratories to Provide High Quality, High Resolution Mass Spectrometry Results
In my last blog post “Re-defining Productivity for Small Molecule, High-resolution Mass Spectrometry Analysis”, I mentioned that Thermo Fisher Scientific recently launched the Thermo Scientific Orbitr...
Re-defining Productivity for Small Molecule, High-resolution Mass Spectrometry Analysis
The moment I committed to a more active lifestyle than my meager 3,000 steps a day, I was instantly in the market for an activity tracker. Primarily, I cared about data accuracy because otherwise what...
2020 Virtual Events – The New Orbitrap Exploris 240 and 120 Mass Spectrometers Drive Discovery and Identification with Quantitative Precision and Accuracy
ASMS looks quite different this year than it has in the past. While we are all experiencing the continuously growing scientific world in a virtual format, there is no shortage of new and exciting inno...
Demystifying UFOs Using PTCR on the Orbitrap Eclipse Tribrid Mass Spectrometer
Confident interpretation of biological mass spectral data is dependent on a priori knowledge and high-quality data. That is, knowing what should be in the sample and being able to extract relevant dat...
Orbitrap Mass Spectrometry and Artificial Intelligence for Bacterial Species Identification in Clinical Research Samples
Arnaud Droit is Associate Professor at Université Laval and director of the Bioinformatics and Proteomics platforms at the Centre de Recherche du CHU de Québec - Université Laval. He is an expert in t...
E-cigarettes – Are they really safe?
Are e-cigarettes really less harmful than conventional cigarettes? Influential health organizations have stated that “e-cigarettes are 95% safer than conventional cigarettes.” This claim originated fr...
Halal Testing and Detection in Complex Matrices: Utilizing the Power of Mass Spectrometry
Dr. Francis Beaudry is an Associate Professor at the veterinary biomedicine department of the Faculty of veterinary medicine of the Université de Montréal. He is an adjunct researcher at the Universit...
Food Allergen Detection in Complex Matrices: Utilizing the Power of Mass Spectrometry
The Food Allergy Research and Resource Program (FARRP) is a food industry-oriented research and outreach program within the Department of Food Science and Technology at the University of Nebraska-Linc...
5 More Reasons to Justify a New LCMS for Your Research Discoveries
In 2013, we changed the paradigm for how our customers were able to approach their research with the introduction of the first Thermo Scientific Orbitrap Tribrid Mass Spectrometer (MS). The Orbitrap T...
What makes the new Orbitrap Exploris 480 extraordinary simplified?
With remarkable robustness the Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer is an advanced, intelligence-driven instrument, built for ultimate performance and ease of use.Data certainty...
ASMS 2019 – Day 2 Recap – New Mass Spectrometer Maximizes Research Insights and Productivity Through Intelligent Data Acquisition Strategies
The second day of ASMS 2019 in Atlanta, GA has come and gone, but the new technology is still as exciting as ever. Scientists in academic, government and biopharmaceutical laboratories faced with incr...
ASMS 2019 – Day 1 Recap – New-Generation Benchtop Mass Spectrometer Advances Quantitative Proteomics and Translational Research
The first day of ASMS 2019 in Atlanta, GA was a success! We’re thrilled to unveil the new compact, benchtop mass spectrometer that unlocks the power of an advanced differential ion mobility interface ...
Top Six Reasons Upgrading Your Small Molecule Structural Elucidation Approach May Be in Order
Whether the mass spectrometry-based approach you use today is tedious and time consuming, doesn’t deliver the confident results you need or you are running low on talent with technical competency, it ...
Ensuring Water Safety: Q&A with an Italian Wastewater Facility
I sat down with Federico Dall’Acqua, LC-MS specialist at Veritas, to discuss how Thermo Scientific Orbitrap mass analyzer technology is being used in water and wastewater treatment facilities which se...
Don’t Be a Fool! Five Things to Consider When Selecting Your Next Research Mass Spectrometer for LFQ
The PursuitPursuit of high-throughput sample phenotyping through label-free quantitation (LFQ) using LC-MS requires substantial instrument performance to enable researchers to evaluate their experimen...
TOF vs. Orbitrap
Choosing the Right Instrument For Intact Protein Structural InsightsThe analysis of intact proteins, such as therapeutic monoclonal antibodies (mAbs) under ‘native’ (non-denaturing) conditions using m...
Purchasing the Right Mass Spectrometer: Triple Quadrupole vs. High-Resolution Accurate Mass Spectrometry
In my last blog post, “Purchasing the Right LCMS: Lessons Learned from Wedding Planning” I encouraged you to think through a couple of key questions around your LCMS instrument purchasing goals. In to...
Making Characterizing Unknowns as Easy as Targeted Quantitation with Orbitrap Technologies
Targeted quantitation workflows, used to screen against a predefined list of known analytes and accurately determine how much is present, play an essential role in safeguarding public health and prote...
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