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Blog Articles

Tips to Prolong the Lifetime of Your HPLC Column

Are your columns not lasting as long as you want? Are you struggling to identify what kills your column or how you can increase its lifetime? A new white paper describes what actions you can take to p...

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Top 5 Reasons for Using µPAC HPLC Columns

At Thermo Fisher Scientific™, we have been at the forefront of proteomic research since the start. With our product and workflow innovations, we have provided researchers with unprecedented possibilit...

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Top 10 AnalyteGuru Blog Posts of 2021

As we close out 2021, the team at AnalyteGuru would like to wish you a safe and happy holiday season. It was an eventful year for us. We grew our analytical science blog into a scientific community, a...

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Don’t Get Lost in Your HPLC Method Development

HPLC method development is a bit like trying to solve a maze. The goal – the cheese, if you will – is to develop a method that provides adequate resolution, sensitivity, robustness and throughput. Sou...

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Accelerating into Pharma 4.0 in the 'Never Normal'

Our world today is anything but normal. In fact, leaders and futurists consider this world the “never normal,” in that everything will always be in flux and what is normal will constantly be redefined...

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What Have Acclaim LC Columns Done for You?

“A new product line?” That was the surprise statement heard around the world when Dionex introduced the first Acclaim HPLC columns 20 years ago, on 10 July, 2001 (later to become the Thermo Scientific...

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How Liquid Chromatography Benefits the Planet

PSA: Climate change is real!Melting glaciers and the extinction of polar bears. Dead coral reefs and acidification of the ocean. Increased droughts and raging wildfires. A warming ocean and stronger h...

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How To Build Your Vanquish HPLC or UHPLC From Scratch

Confused about what HPLC components you need? This guide will teach you how to easily build your HPLC system and request a quote in just a few clicks with the new system configurator tool. As a scient...

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Why Pressure Is Driving Liquid Chromatography Technology

The word pressure is among scientific terms used in our daily life. At least once in life, you have pumped up a ball or balloon. Atmospheric pressure is a weather indicator, and as a car owner, you re...

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Are You Missing Analytes in Your Liquid Chromatography?

I’m sure that is a question that many cannot answer. How do you know if you are missing analytes if you’ve never detected them previously? I am confident, though, that most would wish to have the conf...

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The missing link!

The normal tendency for any analyst is to stay in their comfort zone with HPLC techniques. Sometimes this works, but often not! I see reverse-phase columns forced into application areas which they are...

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5 Ways to Prevent HPLC Method Transfer Failures

“I love using outdated and unreliable instruments,” said no scientist ever.There is nothing more frustrating than spending hours prepping for your experiment only to be shut down because the instrumen...

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The Role of HPLC in Metabolomics

Mass spectrometry-based metabolomics is frequently coupled to a diverse range of chromatographic techniques such as liquid chromatography (LC), ion chromatography (IC), and gas chromatography (GC).I r...

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Why Your Lab Should Upgrade Its HPLC or UHPLC System

Making the switch isn’t always easy, but it’s worth the investment. I vividly remember the day in graduate school when my advisor asked me if I’d be “okay” giving up the HPLC instrument I used for two...

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The Easy Way to Transfer Methods in Liquid Chromatography

During conversations with chromatographers I am frequently asked “how easy is it to transfer a method between different liquid chromatography instruments?”. My usual answer is “it depends”. Before I e...

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The Easy Way to Transfer Methods in Liquid Chromatography

During conversations with chromatographers I am frequently asked, “How easy is it to transfer a method between different liquid chromatography instruments?” My usual answer is, “It depends.” Before I ...

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What are nitrosamines and why should I care?

With one massive, global health concern on everyone’s mind these days, it’s easy to forget that other problems haven’t gone away and may even be just as important or becoming even more critical. They’...

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