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Your educational resource for the latest applications, information and research in sample preparation, chromatography, mass spectrometry, trace elemental analysis and laboratory data management.
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Blog Articles

Don’t Get Lost in Your HPLC Method Development

HPLC method development is a bit like trying to solve a maze. The goal – the cheese, if you will – is to develop a method that provides adequate resolution, sensitivity, robustness and throughput. Sou...

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Accelerating into Pharma 4.0 in the 'Never Normal'

Our world today is anything but normal. In fact, leaders and futurists consider this world the “never normal,” in that everything will always be in flux and what is normal will constantly be redefined...

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How Liquid Chromatography Benefits the Planet

PSA: Climate change is real!Melting glaciers and the extinction of polar bears. Dead coral reefs and acidification of the ocean. Increased droughts and raging wildfires. A warming ocean and stronger h...

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Are You Missing Analytes in Your Liquid Chromatography?

I’m sure that is a question that many cannot answer. How do you know if you are missing analytes if you’ve never detected them previously? I am confident, though, that most would wish to have the conf...

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The Role of HPLC in Metabolomics

Mass spectrometry-based metabolomics is frequently coupled to a diverse range of chromatographic techniques such as liquid chromatography (LC), ion chromatography (IC), and gas chromatography (GC).I r...

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What are nitrosamines and why should I care?

With one massive, global health concern on everyone’s mind these days, it’s easy to forget that other problems haven’t gone away and may even be just as important or becoming even more critical. They’...

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A Short Review of HPLC 2019

The 48th International Symposium on High-Performance Liquid Phase Separation and Related Techniques, or HPLC 2019, concluded yesterday in Milan. It was a fascinating five days in the Italian sunshine,...

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The Finite Lab

We all accept that modern research life requires us to balance creativity with maximizing the return on investment of our instrumentation. In fact, both these demands continue to grow, and at a certai...

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HPLC or UHPLC?

This almost sounds like a line from Shakespeare, but HPLC or high-performance liquid chromatography and ultra-high-performance liquid chromatography (UHPLC) came a little after the ‘Bard of Avon.’ Bot...

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Building Immunity with the Right Tools

Worldwide, researchers are searching for ways to boost the immune system’s ability to fight cancer; one such way is by developing novel therapeutics within the pharmaceutical/biopharmaceutical industr...

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Five Additional Pharmaceutical Impurity Questions

Over the past two months, and during our recent pharmaceutical impurity workshop in Switzerland with LGC Standards, we’ve been asked some additional questions related to pharmaceutical impurities. In ...

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What Is Dual LC and How Does It Benefit Me?

I think we can all generally agree that usually two is better than one: a bicycle is more efficient than a unicycle, two hands or minds are often better than one at completing tasks, etc. Does this tr...

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The Jumbo Jet and HPLC Instruments

You may read the title of this article and wonder how these two are connected as they seem about as far apart as you could possibly imagine. But there are more similarities than you think. And, I beli...

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Chromatographer or Mass Spectrometerist?

Which side of the line do you sit on? Let me break the ice: I sit on the chromatographer side. Most people sit firmly on either side of the line; not many consider themselves to be both. If you ask a ...

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The Power of Standardized Clinical LC-MS/MS

Over the past 10 years, liquid chromatography tandem mass spectrometry (LC-MC/MS) has evolved into a highly efficient and specific analytical method, suitable for a growing range of clinical applicati...

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Incremental Gains and Liquid Chromatography

I’ve recently returned from HPLC 2017 in Prague where a number of different HPLC and UHPLC systems were showcased and discussed in the many excellent scientific presentations. To many, I am sure, ther...

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In vino veritas…or is there?

Latin. in wine there is truth.By definition the “truth in wine” is that we are more likely to say and what we mean once a few glasses of wine have passed our lips. We may be more likely to say what we...

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