After 20 years of working in the pharmaceutical industry scouting active drugs in research to take to market, along with method transfer to the manufacturing site, I have learned that there is no such...
O-glycan profiling provides a wealth of information on pathologies of diseases. However, O-linked glycosylation is challenging to study for many reasons, including glycan heterogeneity, both in terms ...
Glyphosate, the active ingredient in the herbicide Roundup®, is vital for successful crop cultivation. However, although glyphosate is an effective herbicide, it must be carefully monitored to protect...
Winemakers sometimes use malolactic fermentation to create characteristic flavors in wine. However, some strains of the lactic acid bacteria responsible for this process can generate biogenic amines s...
Exposure to chlorate and perchlorate in milk and dairy products can cause harm to human health, with infants and young children particularly at risk. At high concentrations, chlorate and perchlorate a...
Every week I come across a new article relating to pesticides. Just this week I was reading about a peer-reviewed study in Germany that shows glyphosate and dozens of other pesticides can travel throu...
What is a successful marriage? Is it a partnership of a similar kind or the opposite that attracts? Maybe it’s to bring out the best in each other? My parents were married for 65 years. Watching them ...
In my previous blog article on the topic of the role of elemental analysis in making energy greener, I covered lithium-ion batteries. In this second of three articles, I’ll explore the realm of biofue...
Ion Chromatography is a little different from other chromatographic techniques. Some say it is more niche or specialist, and there is nothing wrong with that. I can understand this assumption; ion exc...
Glycoproteins play a key role in many important biological and physiological processes and are increasingly studied as promising therapeutics. However, manufacturing these complex molecules at scale c...
The normal tendency for any analyst is to stay in their comfort zone with HPLC techniques. Sometimes this works, but often not! I see reverse-phase columns forced into application areas which they are...
In Part 1 and Part 2 of this blog series, we touched upon ways ion chromatography (IC) can have more uses in the pharma lab than just for counterion analysis and how it offers a direct approach to pol...
To state the obvious, researching metabolomics is complex! As a still relatively new branch of ‘omics’ researching and understanding the metabolism of living organisms in a wide range of conditions, i...
What are anionic polar pesticides?The presence of anionic polar pesticides in surface and drinking water, food and beverages has become a controversial issue in recent years. Glyphosate, for example, ...
It’s here! However you spend your holiday season, it is a time for family, tradition, giving. It is thought our modern Christmas celebrations were formed in the 19th Century although some have deeper ...
If you’re in the field of metabolomics then ion chromatography (IC) probably isn’t a technique at the forefront of your mind. However many metabolites in the citric acid and glycolysis cycles are ioni...
I’ve been working in the field of Ion Chromatography (IC) for more than 20 years, but in the last 12 months I’ve been spending much of my time discovering the field of Mass Spectrometry (MS). As I tal...
I’m still surprised to hear that reliable methods for the analysis of polar pesticides do not exist. After all, to my mind, residues and contaminants that are polar ionic in nature can always be separ...
Looking at the shelves in the beverage aisle of my grocery store, the number of choices for bottled water is mind-boggling! It’s evidence that bottled water has been one of the fastest growing beverag...
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