The promise of the Multi-Attribute-Method, or MAM, is increased
efficiency and product knowledge through the implementation of mass
spectrometry (MS) in quality control (QC). Industrywide efforts have...
Technological innovation is steadily entering modern testing
laboratories to execute the day-to-day tasks more efficiently. I
discussed in a previous blog post how a lab can benefit from raising the
l...
My need to commute to work has varied over the last few years, but I
have always been able to depend on my car to get me there. I have
maintenance routinely performed, but it is 15 years old and, in c...
The deadline for oral and poster presentation submission for the
Innovation Summit has been extended to 31 July to allow you more time to
share with us and your colleagues what YOU'VE been doing. In S...
It’s something you don’t want to think about but may happen nevertheless
– a disastrous event risking continuous laboratory operations. As
business processes depend on the data generated in the labora...
Maintaining productivity is always a challenge when faced with any
unforeseen circumstance, but forward-thinking and preventative features
can provide resilience, without compromise to security. With ...
For anyone who used Thermo Scientific™ Atlas™ Chromatography Data System
(CDS) over the past couple of decades, I am sure it holds a special
place in your heart, just as it does for us. Atlas software...
In a previous blog post, I talked about the benefit of monitoring
industrial processes to ensure the purity of the various solutions or
reagents used at different stages of production to achieve optim...
If there’s one industry under a magnifying glass, it’s the oil and gas
industry. Production margins are closely watched, and companies are
currently being asked to drastically reduce costs while at th...
“Half of science is putting forth the right questions.” -- Francis
BaconLaboratory operators ask and are asked questions every day: Does
this material meet the specification? Is it fit for its intende...
I’m kicking off a new series of short videos called Charlie Chats, that
will feature experts and everyday users to help you understand a little
more about the chromatography software that is the backb...
Keeping control of a chromatography data system (CDS) is a never-ending
task; but it is a task that must be done in order to adhere to good
practice (GxP) and data integrity guidelines and to keep you...
Whenever you think about a chromatographic analysis it’s easy to think
about the sample, including the corresponding injections, like blanks,
calibration standards and check standards, combined in one...
With many of us changing our normal work patterns and spending more time
working out of a home office, I have a newfound appreciation of the
technology helping me perform my job remotely. Trips into t...
Laboratory scientists and IT experts in industrial, chemical and
pharmaceutical fields are benefiting from improved productivity and
reduced system administration costs with an enterprise chromatograp...
Data integrity frowns upon time travel. Contemporaneous data collection
would be hard to achieve if everyone had a time machine, but last year I
had a unique opportunity to turn back the clock.Sterlin...
Have you ever used a piece of software and thought, “Why does this need
to be so complicated?” I know I have. Thankfully, there has been an
incredible improvement in the last 20 years with respect to ...
It’s really hard to keep everyone happy when it comes to training - it’s
usually a balancing act between achieving high quality training and the
need to get operators running analyses quickly. If you ...
What is your favourite thing about Chromeleon CDS? If you have read any
of my previous blog posts, I’d guess you would think mine is audit
trails or queries.Good guess but you’d be wrong; I love Chrom...
Foreword by Brian Alliston:Surrounded by likeminded industry-leading
Chromeleon CDS users, I had a lightbulb moment at the International
Chromeleon Software Symposium (ICS2018) in Nice last October
.....
Science is great. It’s the common language that we all share at ASMS
2019. I’ve walked multiple miles throughout the convention centre,
visiting posters, listening to talks, meeting with people who ar...
PolyChlorinated Dibenzo-p-Dioxins (PCDDs) and PolyChlorinated Dibenzo
Furans (PCDFs) are two of 12 initial Persistent Organic Pollutants
(POPs) that were first proposed by the Stockholm Convention in ...
In June 2017, during a Medicines and Healthcare products Regulatory
Agency (MHRA) audit I was asked, “Do you use manual integration?” In the
conversation that followed the auditor recognised that ther...
This is the first installment of a regular blog post where Brian
Alliston, Data Integrity Expert and CDS Specialist, from Sterling Pharma
Solutions shares his on-going experiences with Chromeleon CDS....
Does just the thought of upgrading your chromatography data system (CDS)
fill you with dread? When only thinking about revalidating your system,
updating the software, your IT hardware and operating e...
Reading through some recent U.S. FDA Warning Letters to pharma
manufacturers concerning data integrity, I came across a new one
regarding a Chromatography Data System (CDS). There were a couple of
ver...
"You have all these audit trails, which provide great information about
your testing, but none of your procedures tell you to review those audit
trails. I'll expect to see that next time I'm here."Tho...
Well, Pittcon 2018 has come to an end. What an amazing week! We’ve
shared highlights along the way, but I would be amiss if I didn’t share
with you the benefits of these two solutions that debuted at ...
Not so long ago, the food we ate – and when we ate it – were heavily
influenced by the seasons and local climate. But thanks to modern food
supply chains, we take it for granted that our supermarket s...
I’ve recently returned from HPLC 2017 in Prague where a number of
different HPLC and UHPLC systems were showcased and discussed in the
many excellent scientific presentations. To many, I am sure, ther...