While ASMS 2021 in Philadelphia is coming to a close, there are no shortages of announcements coming from a busy week filled with innovations and solutions for scientists in proteomics, biopharmaceutical, pharmaceutical, forensics, environmental, food safety, clinical research, metabolomics and lipidomics.
Announced just this week, labs can now benefit from the newest software releases with streamlined workflows to deliver more comprehensive analysis of their data, with new features that enable researchers to achieve more high-quality results and increased ease of use and performance.
Deep learning tools to transform proteomics data analysis
The newest Thermo Scientific Proteome Discoverer 3.0 software combines with the CHIMERYS search engine by MSAID to allow Thermo Scientific Orbitrap mass spectrometer users to more fully interpret the data generated by their instruments. Artificial intelligence (AI) enables a deeper mining of proteomics data, which substantially increases the identification of unique peptides and improves overall protein coverage. Proteome Discoverer 3.0 software also includes an updated INFERYS prediction model, the Comet search engine, and a SureQuant method exporter node.
New peak detection and filtering improves and accelerates untargeted small molecule workflows
Small molecule researchers can now benefit from Thermo Scientific Compound Discoverer 3.3 software to detect more compounds in less time, thanks to faster and more sensitive peak detection. The new software provides peak quality reporting to help determine and filter relevant compounds, streamlining the data review process. Scientists can improve confidence in compound annotations through MSn spectral tree search capabilities in tandem with the Thermo Scientific mzCloud spectral library to address the most challenging unknown compounds. Compound Discoverer 3.3 software, which has been optimized for processing large datasets and detecting low-abundance compounds, will support scientists in metabolomics, pharmaceutical, environmental, food safety, clinical research and forensics applications to acquire the results they need to drive science forward.
Simplify comprehensive biotherapeutic attribute characterization workflows
Apply advanced new capabilities for biotherapeutic workflows with Thermo Scientific BioPharma Finder 5.0 software to speed time to results. Increase throughput and confidence with built-for-purpose data processing, curation, and customizable reporting in a secure connected environment to streamline and enable collaboration on a global scale. Scientists can leverage BioPharma Finder software across multiple application workflows and modalities including peptide mapping analysis, oligonucleotide analysis, intact mass analysis and top down analysis for increased confidence and productivity.
Improved performance and customization for lipid-profiling software
Thermo Scientific LipidSearch 5.0 software offers a completely new and improved graphical user interface with an improved retention time correction algorithm, new ms2 deconvolution functionality, and extensive and readily customizable lipid database containing over 1.5 million lipids and their predicted fragment ions. LipidSearch 5.0 software also now supports direct-infusion workflows with new qualitative and quantitative features to extend the processing capabilities for both liquid chromatography and shotgun lipidomics workflows. These improvements provide added identification confidence, better quantitative performance, and streamline lipidomics data analysis with ease of use improvements.