Another day of ASMS 2021 is on the books with more exciting new innovations for biopharmaceutical laboratories. Labs can now benefit from high-quality mass information delivered by Orbitrap technology for molecule attribute monitoring in development and quality control (QC). This offering is a part of a multi-attribute method (MAM) workflow that offers reduced downtime and maintenance and provides seamless method transfers from development to QC.
The Thermo Scientific Orbitrap Exploris MX mass detector offers high-resolution accurate mass (HRAM) data for intact analysis of monoclonal antibodies (mAbs), oligonucleotide mass determination and peptide mapping, making it ideal for biopharma process confirmation. This enables accelerated drug characterization processes in QC and productivity improvements by fully integrating the Orbitrap Exploris MX into the MAM 2.0 workflow, thereby replacing multiple assays into one information-rich mass spectrometric assay. Additionally, the hardware and software transition from using the Thermo Scientific Orbitrap Exploris 240 mass spectrometer in development stage to using the Orbitrap Exploris MX mass detector in QC stage is made seamless by the compliance-ready Thermo Scientific Chromeleon chromatography data system (CDS) software.
Other advantages of the Orbitrap Exploris MX include:
Easy adoption for contract research, development and manufacturing organizations enabled by rapid calibration procedures, built-in methods, and reliable performance
Orbitrap technology which provides market-leading resolution, mass accuracy and sensitivity.