The 2017 ASMS storm has passed, the dust has settled and the a leading technology in protein analysis and biopharma characterization has emerged. In my opinion, the novel Thermo Scientific Q Exactive HF-X hybrid quadrupole mass spectrometer is undoubtedly the must-have mass spectrometer for discovery proteomics, translational proteomics and biopharma characterization in your lab.
Understanding biomolecules as drug targets, disease markers, and therapeutic agents demands highly sensitive analysis of complex biological samples, without sacrificing robustness and speed. The Q Exactive HF-X rises to the challenge as a versatile platform, setting new standards in sensitivity, performance and productivity for many workflows. Building on the proven performance of the Thermo Scientific Q Exactive HF hybrid quadrupole-Orbitrap MS instrument, the new Q Exactive HF-X mass spectrometer couples a high field Thermo Scientific Orbitrap mass analyzer with a high capacity transfer tube and electrodynamic ion funnel that maximizes ion loading and transmits ions over a broad mass range.
As a result, the instrument delivers a bright, focused and ion-rich beam, which translates to high sensitivity and excellent stability in analysis quality from run to run. Smart instrument control features match the superior ion transmission with increased acquisition speed and even more sophisticated data-dependent acquisition. Additionally, analysis strategies meet data quality needs at every stage of your work, from discovery to verification and quantitation.
The Q Exactive HF-X is the new top-of-the line product in the portfolio of Q Exactive instruments and features innovations such as:
A high capacity transfer tube for increased sensitivity
Faster scan capabilities -- up to 40 Hz in MS/MS
Optimized scan matrix with accelerated HCD
Advanced DDA strategies
and other improvements for increased productivity in targeted peptide quantitation