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Can You CAD it? Yes You Can …

Team TFS
Team TFS



2021 Charged Aerosol Detection Symposium

Wow, what a fantastic Charged Aerosol Detection (CAD) Symposium. You won’t want to miss the on-demand series or next year’s symposium!

If you want to discover hidden peaks and are you looking for a sensitive, universal detection method with near-uniform response independent of the chemical structure, if any of your analytes lack chromophores and you need to run non-volatile and semi-volatile analysis down to sub-nanogram levels, then this on-demand symposium is for you.

Typically, we run the CAD symposium in separate regions as face-to-face events,  but this year for the first time we were virtual, globally. What an experience for everyone involved. The reaction and ­engagement between our speakers and the audience was incredible; I’ve have never seen so many questions come up during a webinar.

Learn more about CAD

Charged aerosol detection measures analytes that cannot be seen by UV and may not readily be detected with other detection techniques. Join the on-demand sessions and dive into the technical capabilities of this unique HPLC detector, discover the extent of its use, and see how easily CAD works with any HPLC system, regardless of provider.

A wide range of detection options exist for liquid chromatography, but each has limitations. Charged aerosol detection offers an alternative, universal detection option. Watch these presentations in Session 1 to find out more:

Basics and beyond: Chris Tuczemskyi - Thermo Fisher Scientific

Polysorbate analysis in drug products: Georg Schuster - Coriolis Pharma

CAD in Pharmaceutical Analysis – Selected applications and optimization strategies: Ruben Pawellek - University of Wüzburg

High throughput analysis (HTA) for small molecule libraries with the Thermo Scientific Vanquish Duo UHPLC system: Thomas Dann and Matthew Gill - Charles River Laboratories

With the flexibility and performance for analytical R&D, and the simplicity and reproducibility needed for manufacturing QA/QC, charged aerosol detection can be used for the analysis of pharmaceuticals (large and small molecule). Session 2 speakers from Pharma giants:

Peptide Quantification by CAD: Kilian Conde Frieboes - Novo Nordisk

How CAD enabled universal quantification in a high-throughput library purification platform: Marcel Reck - Novartis Institute for Biomedical Research

LC-charged aerosol detector in early and late-stage pharmaceutical development: Selection of regression models at optimum power function value: Imad Haidar Ahmad - Merck Research Laboratories

With special guest Ulrike Holzgrabe, Institut für Pharmazie und Lebensmittelchemie University of Würzburg

Did you know that CAD can be used in application areas such as food and beverage, in lipid analysis for food fraud and for sugar fingerprinting? It’s also used to detect specialty chemicals and polymers, such as the environmentally toxic agent polyacrylic acid. Listen to session 3 for industrial application presentations:

CAD Tips and Tricks: Paul Gamache - Thermo Fisher Scientific

A UHPLC-PDA-CAD-HRMS Platform for Comprehensive Identification and Quantitation of Constituents in Complex Mixtures for Safety Risk Assessments: Dr. Jason Price - Procter & Gamble R&D

Using UHPLC-CAD and PCA to detect olive oil adulteration via triacylglycerol analysis: Hilary Green - UC Davis

To find out more about charged aerosol detection, visit our downloadable resources here and read these articles by Tim Cross and Jenny Wong.