The week is flying by at ASMS 2021 in Philadelphia and the latest innovations continue to roll out for biopharmaceutical laboratories working across R&D, manufacturing and quality control (QC) environments. Labs can now streamline biopharmaceutical characterization, process monitoring and release testing using a new seamless, built-for-purpose multi-attribute method (MAM) workflow.
The Thermo Scientific MAM 2.0 workflow is a culmination of collaborations and conversations with industry leaders that led to features added specifically to address MAM user needs. The result is an end-to-end, single vendor solution providing a holistic ecosystem for implementation from biotherapeutic development through to quality control (QC). The MAM 2.0 solution enables direct connectivity in both hardware and software through all stages of development and manufacturing.
The workflow manages all analytical processes from instrument control to data management through a secure, integrated software ecosystem, streamlining the process from development to QC. The Thermo Scientific BioPharma Finder 5.0 software provides MAM users with fit-for-purpose enhancements for confident attribute characterization, data security and integrity, customizable reporting, and team collaboration at a global scale. From instrument control, to data storage and processing, through to result generation, Thermo Scientific Chromeleon Chromatography Data System 7.3.1 software manages the analytical processes and enables a simple transfer of the entire MAM workflow from development to QC.
The benefits continue with a consistent technology platform between the Thermo Scientific Orbitrap Exploris 240 mass spectrometer in development and the new Thermo Scientific Orbitrap Exploris MX mass detector, specifically designed for QC applications. Both solutions together will future proof customer needs and enable consistent unit-to-unit performance, while continuing to offer the power of Orbitrap technology. MAM 2.0 also includes training, on-going support, and relationships with laboratories to bring their next biotherapeutic candidate straight through to breakthrough.