ASMS 2017 – Day 3 – Offering Greater Quantitative Sensitivity, Speed and Reproducibility

[mbromirski]

Here we are on day three of ASMS 2017 and the exciting new technology being introduced at the show has the show floor buzzing. The new mass spectrometer platform -- Thermo Scientific Q Exactive HF-X Hybrid Quadrupole Orbitrap mass spectrometer -- is setting new standards for depth of analysis, quantitative accuracy and reproducibility, enabling scientists to advance disease research and drug discovery. The new Q Exactive HF-X platform includes technical advances meant to deliver significant performance improvements, making it the new flagship of the Q Exactive mass spectrometer product family.

Scientists studying complex protein samples can now utilize this new high-performing Orbitrap mass spectrometer designed to quickly and consistently produce superior data quality for challenging workflows across life science research and biopharma applications. For R&D scientists, the instrument delivers extremely fast and accurate mass analysis, plus two-to-three-fold sensitivity improvements, delivering the same number of protein identifications in half of the time required for previous models. For biopharma scientists, the Q Exactive HF-X instrument provides up to eight times better signal to noise ratio for native, intact monoclonal antibody mass determination, glycoprofiling and purity checks.

For more information, visit http://www.thermofisher.com/asms or stop by the Thermo Fisher Scientific booth #601 at ASMS to learn more about the whole workflow that includes:

• The Thermo Scientific UltiMate 3000 RSLCnano system, designed for nano, capillary and micro-flow applications requiring high-sensitivity and throughput


• The Thermo Scientific EASY-Spray PepMap 15cm x 150µm Capillary column, designed for robust and reliable separations


• Biognosys Spectronaut Pulsar software, now compatible with the Q Exactive HF-X instrument as well as previous Orbitrap instruments. It allows researchers to conduct data-independent analysis using MS1 quantitation for reproducible and accurate quantitation of thousands of proteins in a single run


• And Thermo Scientific Proteome Discoverer 2.2 software meant for label-free quantitation, which offers reproducibility across experiments and extensive identification and quantification of proteins